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Visual rating and volumetry of the medial temporal lobe on magnetic resonance imaging in dementia
  1. Laboratory of Epidemiology and Neuroimaging
  2. IRCCS San Giovanni di Dio-FBF, via Pilastroni 1, 25123 Brescia,

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    The paper by Wahlund et al in this issue (pp630–635)1 tries to shed light on the usefulness of biological markers in the routine diagnosis of Alzheimer's disease. Tissue loss in the medial temporal lobe regions as detected by MRI is one of the most feasible and accurate markers developed to date and investigating its usefulness in a clinical setting is potentially relevant.

    The paper has two main merits. Firstly, it highlights that the usefulness of diagnostic examinations needs to be judged within the specific diagnostic pathway.2 For any given patient coming to medical …

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