The dynamics of drug treatment in epilepsy: an observational study in an unselected population based cohort with newly diagnosed epilepsy followed up prospectively over 11–14 years

S D Lhatoo; J W A S Sander; S D Shorvon

doi:10.1136/jnnp.71.5.632

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Paper

The dynamics of drug treatment in epilepsy: an observational study in an unselected population based cohort with newly diagnosed epilepsy followed up prospectively over 11–14 years

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	Abstract	Full	Pdf
Oct 2001	134	109	30
Nov 2001	195	112	30
Dec 2001	50	36	7
Jan 2002	27	44	6
Feb 2002	15	36	14
Mar 2002	18	32	4
Apr 2002	16	27	5
May 2002	10	15	12
Jun 2002	5	5	6
Jul 2002	6	19	10
Aug 2002	2	14	10
Sep 2002	7	14	2
Oct 2002	6	12	7
Nov 2002	7	31	28
Dec 2002	7	16	13
Jan 2003	5	35	70
Feb 2003	4	40	19
Mar 2003	2	12	5
Apr 2003	3	16	20
May 2003	5	15	9
Jun 2003	1	6	4
Jul 2003	5	8	3
Aug 2003	3	10	11
Sep 2003	3	14	4
Oct 2003	6	17	4
Nov 2003	4	12	13
Dec 2003	1	6	11
Jan 2004	1	7	2
Feb 2004	1	11	13
Mar 2004	0	17	15
Apr 2004	0	8	7
May 2004	2	5	4
Jun 2004	5	8	9
Jul 2004	44	65	18
Aug 2004	41	59	23
Sep 2004	26	44	15
Oct 2004	11	32	23
Nov 2004	9	36	18
Dec 2004	7	20	13
Jan 2005	19	16	7
Feb 2005	14	14	12
Mar 2005	17	27	9
Apr 2005	8	12	9
May 2005	5	19	10
Jun 2005	2	10	6
Jul 2005	2	6	4
Aug 2005	4	21	11
Sep 2005	5	13	15
Oct 2005	15	27	27
Nov 2005	10	24	6
Dec 2005	8	34	18
Jan 2006	8	25	10
Feb 2006	7	19	7
Mar 2006	4	18	12
Apr 2006	5	28	12
May 2006	4	15	11
Jun 2006	10	20	12
Jul 2006	6	19	10
Aug 2006	1	3	2
Sep 2006	16	25	25
Oct 2006	7	27	16
Nov 2006	6	26	12
Dec 2006	9	21	9
Jan 2007	4	20	12
Feb 2007	2	20	12
Mar 2007	8	19	11
Apr 2007	21	5	6
May 2007	15	9	4
Jun 2007	13	7	6
Jul 2007	19	13	3
Aug 2007	5	5	3
Sep 2007	12	5	6
Oct 2007	14	5	6
Nov 2007	10	8	10
Dec 2007	4	2	2
Jan 2008	5	7	4
Feb 2008	6	0	0
Mar 2008	20	8	9
Apr 2008	12	3	6
May 2008	6	9	0
Jun 2008	4	1	2
Jul 2008	15	3	8
Aug 2008	9	4	6
Sep 2008	9	0	1
Oct 2008	3	1	2
Nov 2008	6	4	1
Dec 2008	3	4	5
Jan 2009	11	0	1
Feb 2009	5	1	3
Mar 2009	4	5	2
Apr 2009	11	0	1
May 2009	4	0	1
Jun 2009	5	2	1
Jul 2009	9	1	2
Aug 2009	4	3	1
Sep 2009	6	2	5
Oct 2009	9	3	3
Nov 2009	9	1	2
Dec 2009	6	0	0
Jan 2010	9	5	7
Feb 2010	4	4	3
Mar 2010	7	1	1
Apr 2010	7	2	1
May 2010	5	0	0
Jun 2010	6	3	4
Jul 2010	4	3	1
Aug 2010	1	1	2
Sep 2010	3	3	0
Oct 2010	15	4	2
Nov 2010	11	0	3
Dec 2010	4	6	2
Jan 2011	7	4	1
Feb 2011	12	2	0
Mar 2011	13	0	0
Apr 2011	8	0	3
May 2011	13	4	2
Jun 2011	15	1	0
Jul 2011	8	1	0
Aug 2011	14	1	1
Sep 2011	5	1	3
Oct 2011	15	2	5
Nov 2011	23	8	4
Dec 2011	7	17	8
Jan 2012	21	23	6
Feb 2012	7	25	3
Mar 2012	15	18	6
Apr 2012	10	12	7
May 2012	8	21	3
Jun 2012	16	11	4
Jul 2012	11	22	9
Aug 2012	10	21	9
Sep 2012	15	27	9
Oct 2012	17	33	12
Nov 2012	23	26	8
Dec 2012	16	7	6
Jan 2013	15	15	11
Feb 2013	28	4	4
Mar 2013	18	15	8
Apr 2013	28	5	5
May 2013	7	9	7
Jun 2013	12	3	3
Jul 2013	10	7	2
Aug 2013	7	3	2
Sep 2013	14	6	1
Oct 2013	8	8	8
Nov 2013	22	6	8
Dec 2013	5	5	10
Jan 2014	7	4	1
Feb 2014	5	4	4
Mar 2014	8	2	5
Apr 2014	26	6	5
May 2014	22	7	6
Jun 2014	15	3	9
Jul 2014	17	4	10
Aug 2014	17	6	11
Sep 2014	7	6	11
Oct 2014	3	3	7
Nov 2014	13	7	10
Dec 2014	3	6	10
Jan 2015	8	2	6
Feb 2015	10	3	7
Mar 2015	19	2	6
Apr 2015	14	10	6
May 2015	16	5	3
Jun 2015	8	3	0
Jul 2015	7	2	0
Aug 2015	7	5	8
Sep 2015	15	4	2
Oct 2015	6	2	0
Nov 2015	7	3	3
Dec 2015	10	1	0
Jan 2016	9	4	0
Feb 2016	10	4	5
Mar 2016	11	3	3
Apr 2016	10	0	2
May 2016	8	3	3
Jun 2016	10	0	0
Jul 2016	5	5	2
Aug 2016	15	2	1
Sep 2016	13	11	4
Oct 2016	16	3	3
Nov 2016	11	7	4
Dec 2016	10	1	1
Jan 2017	11	1	0
Feb 2017	2	8	2
Mar 2017	4	6	1
Apr 2017	1	8	1
May 2017	1	7	2
Jun 2017	6	7	1
Jul 2017	5	2	2
Aug 2017	14	6	6
Sep 2017	16	8	2
Oct 2017	11	7	3
Nov 2017	9	9	4
Dec 2017	5	1	2
Jan 2018	9	5	2
Feb 2018	12	10	4
Mar 2018	17	9	5
Apr 2018	14	12	0
May 2018	16	10	0
Jun 2018	54	48	0
Jul 2018	9	5	2
Aug 2018	8	4	1
Sep 2018	8	6	2
Oct 2018	9	7	4
Nov 2018	11	9	4
Dec 2018	11	11	0
Jan 2019	6	6	0
Feb 2019	12	12	5
Mar 2019	10	10	5
Apr 2019	11	7	6
May 2019	6	6	3
Jun 2019	5	5	2
Jul 2019	12	10	4
Aug 2019	9	9	3
Sep 2019	5	5	4
Oct 2019	11	11	5
Nov 2019	10	11	11
Dec 2019	10	10	8
Jan 2020	10	10	4
Feb 2020	3	3	6
Mar 2020	3	3	2
Apr 2020	11	11	2
May 2020	9	9	3
Jun 2020	20	18	6
Jul 2020	8	8	4
Aug 2020	3	3	5
Sep 2020	19	17	6
Oct 2020	12	12	4
Nov 2020	18	12	5
Dec 2020	14	14	3
Jan 2021	18	13	8
Feb 2021	14	12	6
Mar 2021	9	5	2
Apr 2021	5	5	3
May 2021	10	9	1
Jun 2021	16	16	4
Jul 2021	8	8	6
Aug 2021	14	14	2
Sep 2021	17	17	9
Oct 2021	20	20	16
Nov 2021	12	12	12
Dec 2021	6	6	2
Jan 2022	9	9	7
Feb 2022	11	11	1
Mar 2022	20	19	7
Apr 2022	15	15	6
May 2022	26	26	12
Jun 2022	23	22	3
Jul 2022	18	18	1
Aug 2022	21	21	5
Sep 2022	27	27	16
Oct 2022	25	25	1
Nov 2022	14	12	5
Dec 2022	9	8	10
Jan 2023	19	12	4
Feb 2023	26	26	1
Mar 2023	13	13	0
Apr 2023	5	5	5
May 2023	11	13	5
Jun 2023	11	9	1
Jul 2023	18	18	9
Aug 2023	9	9	3
Sep 2023	22	24	5
Oct 2023	25	27	2
Nov 2023	16	14	2
Dec 2023	133	21	2
Jan 2024	47	0	0
Feb 2024	33	1	1
Mar 2024	101	2	2
Total	3507	3194	1641

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