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Hypothalamic involvement in chronic migraine
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  • Published on:
    Re: Hypercortisolemia and chronic migraine

    Dear Dr Eugene Cassidy,

    Thanks for your letter and comments.

    The Beck Depression Inventory (BDI) scores were not correlated with cortisol levels in our study. In addition, cortisol levels in patients with BDI score higher than 16 (and 21) were not different from those with score 16 (and 21) or lower.

    We agree hypercortisolemia is a feature of CM with co-morbid depression, and not CM alone, ho...

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    Conflict of Interest:
    None declared.
  • Published on:
    Hypercortisolemia and chronic migraine

    Dear Editor

    Peres et al (2001) are to be congratulated for advancing the limited neuroendocrine literature on chronic migraine, a disorder with a significant attendant morbidity and a poorly understood pathophysiology.

    A few points however deserve mention.

    In their introduction, the authors rightly highlight that chronic migraine (CM) and major depression are strongly associated. However, in this...

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    Conflict of Interest:
    None declared.