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Hypertension+MRI changes=impaired cognition
  1. S Tuhrim,
  2. S R Levine
  1. The Stroke Program, Department of Neurology, The Mount Sinai School of Medicine, New York, USA
  1. Correspondence to:
 Dr S R Levine, Stroke Program, Department of Neurology, Box 1137, The Mount Sinai School of Medicine, One Gustave L Levy Place, New York 10029–6574, USA;
 steven.levine{at}mssm.edu

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A quantifiable formula?

As both the average age of the population and rates of vascular dementia increase, there has been keen interest in measuring and quantifying determinants of cognitive impairment. Koga et al (this issue pp 737–741)1 quantify brain MRI abnormalities and relate them to loss of a normal mental state in a single rural, independent, elderly community. Cognitive impairment was defined as a mini mental state examination (MMSE) score <24 with a mean study score of 26 points.1

The work exemplifies the expanding body of investigations utilising increasingly complex MRI techniques and data analyses to provide insights into brain function beyond those obtainable …

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