Article Text
Book review
Channelopathies of the nervous system
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Edited by M R Rose and RC Griggs (Pp 347, £60.00). Published by Butterworth Heinemann, Oxford, 2001. ISBN 0-7506-4507-5
Over the past few years there has been an explosion of knowledge regarding a group of diseases that have become known as the channelopathies. Like many new chapters of medical discovery it always seems obvious in retrospect. After all, ion channels are one of the most critical structures for normal neural activity. This cascade of new knowledge has now firmly established that dysfunction of both ligand gated and voltage gated ion channels may cause human diseases. The dysfunction either may be …