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Diagnostic value of nystagmus: spontaneous and induced ocular oscillations
  1. Dr R J Leigh, Department of Neurology, University Hospitals, 11100 Euclid Avenue, Cleveland, Ohio, 44106–5000, USA;
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Serra A, Leigh RJ
Diagnostic value of nystagmus: spontaneous and induced ocular oscillations

Publication history

  • First published December 1, 2002.
Online issue publication 
December 01, 2002
    Diagnostic value of nystagmus: spontaneous and induced ocular oscillations
    A Serra and R J Leigh

    Video Clips

    Video Sequence 1: Congenital Nystagmus
    Note how this horizontal, jerk-pendular form of idiopathic congenital nystagmus remains horizontal even in upgaze
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    File size: 1.51 MB

    Video Sequence 2: Downbeat Nystagmus
    In this patient with multiple sclerosis, downbeat nystagmus is most apparent when he looks laterally and downward
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    File size: 1.34 MB

    Video Sequence 3: Gaze & Rebound Nystagmus
    In this patient with a cerebellar degeneration, there is gaze-evoked nystagmus on far right gaze, and rebound nystagmus when the eyes return to central position
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    File size: 1.18 MB

    Video Sequence 4: Latent Nystagmus
    This patient, with exotropia since childhood, had right-beating nystagmus when the left eye was covered and left-beating nystagmus when the right eye was covered
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    File size: 1.5 MB

    Video Sequence 5: Macrosaccadic Oscillations
    This patient, who has a recently reported cerebellar degeneration,24 shows marked saccadic hypermetria with some episodes of sustained saccadic oscillations around the desired fixation point. These oscillations have intersaccadic intervals (see Fig 1F)
    [View Video]
    File size: 1.47 MB

    Video Sequence 6: Opsoclonus
    This patient with paraneoplastic opsoclonus shows a burst of high-frequency saccadic oscillations (without intersaccadic intervals � see Fig 1G) following an upward saccade. These oscillations consist of eye rotations with horizontal, vertical and torsional components
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    File size: 1.26 MB

    Video Sequence 7: Pendular Nystagmus
    This patient with multiple sclerosis has predominantly pendular oscillations at about 4 cycles/second that have both horizontal and vertical components, with superimposed horizontal jerk nystagmus
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    File size: 980 KB

    Video Sequence 8: Seesaw Nystagmus
    Congenital form with oppositely directed vertical oscillations as well as intorsion of the elevating eye and extorsion of the depressing eye
    [View Video]
    File size: 1.02 MB

    Video Sequence 9: Upbeat Nystagmus
    In this patient with multiple sclerosis, oscillopsia and vertigo were the presenting symptoms
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    File size: 1.18 MB

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