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Peripheral nerve granuloma in a patient with tuberculosis
  1. R W Orrell1,2,
  2. R H M King1,
  3. J V Bowler1,2,3,
  4. L Ginsberg1,2
  1. 1University Department of Clinical Neurosciences, Royal Free and University College Medical School, University College London, London, UK
  2. 2Department of Neurology, Royal Free Hospital, London, UK
  3. 3North Middlesex Hospital, London, UK
  1. Correspondence to:
 Dr R W Orrell, Department of Clinical Neurosciences, Royal Free and University College Medical School, University College London, Rowland Hill Street, London NW3 2PF, UK;
 r.orrell{at}rfc.ucl.ac.uk

Abstract

The cause of peripheral neuropathy associated with tuberculosis is controversial. Possibilities include an immune mediated neuropathy, direct invasion of nerves, vasculitic neuropathy, compressive neuropathy, a meningitic reaction, and the toxic effects of antituberculous chemotherapy. This report describes the unusual finding of granulomas in the peripheral nerve of a patient with tuberculosis. The pathological findings were of a delayed hypersensitivity reaction, but with no more specific indications of the mechanism of the neuropathy.

  • tuberculosis
  • neuropathy
  • granuloma

https://doi.org/10.1136/jnnp.73.6.769

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    Footnotes

    • Competing interests: none declared.