Hypocretin (orexin) deficiency in narcolepsy and primary hypersomnia

I O Ebrahim; M K Sharief; S de Lacy; Y K Semra; R S Howard; M D Kopelman; A J Williams

doi:10.1136/jnnp.74.1.127

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Hypocretin (orexin) deficiency in narcolepsy and primary hypersomnia

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	Abstract	Full	Pdf
Dec 2002	54	91	36
Jan 2003	36	168	53
Feb 2003	12	95	39
Mar 2003	8	65	29
Apr 2003	12	64	19
May 2003	5	31	13
Jun 2003	4	21	12
Jul 2003	3	19	3
Aug 2003	14	28	5
Sep 2003	12	17	6
Oct 2003	7	22	5
Nov 2003	6	23	10
Dec 2003	4	17	6
Jan 2004	9	27	21
Feb 2004	14	21	26
Mar 2004	11	23	15
Apr 2004	7	20	17
May 2004	7	18	13
Jun 2004	14	26	12
Jul 2004	47	71	19
Aug 2004	45	70	14
Sep 2004	44	142	15
Oct 2004	23	71	23
Nov 2004	23	86	51
Dec 2004	41	84	41
Jan 2005	49	80	41
Feb 2005	22	56	22
Mar 2005	44	77	44
Apr 2005	13	53	11
May 2005	18	47	16
Jun 2005	17	46	20
Jul 2005	15	30	10
Aug 2005	14	49	13
Sep 2005	19	25	16
Oct 2005	21	56	37
Nov 2005	33	58	25
Dec 2005	13	46	14
Jan 2006	9	71	25
Feb 2006	11	36	10
Mar 2006	33	57	26
Apr 2006	17	42	19
May 2006	19	39	9
Jun 2006	23	29	6
Jul 2006	15	29	17
Aug 2006	13	29	12
Sep 2006	10	29	15
Oct 2006	26	43	16
Nov 2006	30	37	35
Dec 2006	25	56	26
Jan 2007	25	32	22
Feb 2007	15	39	27
Mar 2007	20	52	29
Apr 2007	36	8	8
May 2007	26	13	8
Jun 2007	15	13	9
Jul 2007	23	10	5
Aug 2007	152	7	6
Sep 2007	72	14	11
Oct 2007	94	4	14
Nov 2007	53	16	12
Dec 2007	34	6	3
Jan 2008	183	10	1
Feb 2008	76	5	12
Mar 2008	37	4	3
Apr 2008	43	6	7
May 2008	20	2	4
Jun 2008	14	8	4
Jul 2008	17	9	5
Aug 2008	42	7	5
Sep 2008	35	9	7
Oct 2008	30	2	1
Nov 2008	41	4	10
Dec 2008	19	4	2
Jan 2009	18	4	4
Feb 2009	14	7	3
Mar 2009	33	5	3
Apr 2009	18	11	6
May 2009	18	2	4
Jun 2009	19	0	0
Jul 2009	23	1	0
Aug 2009	18	2	0
Sep 2009	15	1	1
Oct 2009	23	8	4
Nov 2009	34	3	2
Dec 2009	28	3	3
Jan 2010	16	5	7
Feb 2010	30	9	8
Mar 2010	23	2	2
Apr 2010	32	5	2
May 2010	35	4	3
Jun 2010	33	2	2
Jul 2010	37	6	1
Aug 2010	23	6	4
Sep 2010	34	7	6
Oct 2010	47	5	2
Nov 2010	45	10	3
Dec 2010	37	8	6
Jan 2011	26	2	6
Feb 2011	31	5	4
Mar 2011	42	1	0
Apr 2011	23	9	4
May 2011	31	3	4
Jun 2011	16	4	3
Jul 2011	13	0	0
Aug 2011	32	1	2
Sep 2011	21	3	2
Oct 2011	46	5	1
Nov 2011	37	22	8
Dec 2011	23	25	8
Jan 2012	20	26	10
Feb 2012	14	46	12
Mar 2012	22	46	14
Apr 2012	18	49	21
May 2012	27	83	10
Jun 2012	11	35	6
Jul 2012	13	57	15
Aug 2012	11	64	5
Sep 2012	13	71	7
Oct 2012	19	74	11
Nov 2012	32	79	22
Dec 2012	28	64	10
Jan 2013	24	106	18
Feb 2013	21	77	7
Mar 2013	22	59	9
Apr 2013	35	83	22
May 2013	20	52	18
Jun 2013	12	49	7
Jul 2013	10	47	6
Aug 2013	15	49	9
Sep 2013	11	78	176
Oct 2013	16	114	24
Nov 2013	25	127	35
Dec 2013	15	114	22
Jan 2014	10	104	12
Feb 2014	14	93	11
Mar 2014	22	73	14
Apr 2014	25	145	17
May 2014	10	150	11
Jun 2014	8	161	11
Jul 2014	10	172	17
Aug 2014	9	171	20
Sep 2014	4	198	8
Oct 2014	17	123	7
Nov 2014	16	88	6
Dec 2014	15	72	6
Jan 2015	15	114	16
Feb 2015	12	103	5
Mar 2015	21	192	20
Apr 2015	23	193	29
May 2015	20	209	8
Jun 2015	26	152	12
Jul 2015	21	190	9
Aug 2015	14	172	6
Sep 2015	15	181	4
Oct 2015	11	122	7
Nov 2015	15	208	10
Dec 2015	10	212	5
Jan 2016	17	173	8
Feb 2016	10	175	10
Mar 2016	16	183	13
Apr 2016	14	206	7
May 2016	19	153	17
Jun 2016	9	134	11
Jul 2016	9	144	4
Aug 2016	5	155	7
Sep 2016	17	149	8
Oct 2016	17	221	11
Nov 2016	16	288	8
Dec 2016	12	207	5
Jan 2017	10	232	6
Feb 2017	8	160	7
Mar 2017	7	159	8
Apr 2017	3	226	15
May 2017	1	254	19
Jun 2017	55	195	11
Jul 2017	148	147	5
Aug 2017	139	139	5
Sep 2017	174	168	6
Oct 2017	290	283	10
Nov 2017	255	239	13
Dec 2017	131	118	6
Jan 2018	142	134	7
Feb 2018	164	141	12
Mar 2018	160	156	10
Apr 2018	156	144	1
May 2018	153	134	18
Jun 2018	132	129	4
Jul 2018	140	122	6
Aug 2018	203	203	9
Sep 2018	190	184	8
Oct 2018	237	225	15
Nov 2018	250	238	14
Dec 2018	183	179	11
Jan 2019	220	218	7
Feb 2019	235	228	10
Mar 2019	219	206	20
Apr 2019	242	238	17
May 2019	204	200	11
Jun 2019	197	195	13
Jul 2019	196	195	24
Aug 2019	192	190	9
Sep 2019	203	193	3
Oct 2019	209	198	8
Nov 2019	208	198	25
Dec 2019	200	198	12
Jan 2020	235	222	21
Feb 2020	220	218	17
Mar 2020	164	159	15
Apr 2020	93	84	5
May 2020	104	98	13
Jun 2020	100	98	5
Jul 2020	113	104	13
Aug 2020	88	86	10
Sep 2020	130	130	6
Oct 2020	183	175	16
Nov 2020	202	201	21
Dec 2020	189	185	13
Jan 2021	211	207	8
Feb 2021	173	171	9
Mar 2021	172	170	12
Apr 2021	152	152	12
May 2021	273	272	18
Jun 2021	141	145	17
Jul 2021	126	126	7
Aug 2021	162	163	11
Sep 2021	157	158	17
Oct 2021	163	165	29
Nov 2021	77	77	24
Dec 2021	145	156	7
Jan 2022	126	133	15
Feb 2022	115	121	9
Mar 2022	167	172	12
Apr 2022	152	161	16
May 2022	148	149	33
Jun 2022	98	95	10
Jul 2022	72	72	10
Aug 2022	141	113	5
Sep 2022	206	207	9
Oct 2022	169	171	14
Nov 2022	198	193	15
Dec 2022	165	157	9
Jan 2023	141	142	4
Feb 2023	168	166	7
Mar 2023	179	179	9
Apr 2023	156	158	11
May 2023	163	164	13
Jun 2023	181	187	3
Jul 2023	204	203	10
Aug 2023	172	160	13
Sep 2023	164	162	13
Oct 2023	136	136	7
Nov 2023	174	175	6
Dec 2023	257	41	0
Jan 2024	45	2	0
Feb 2024	126	1	1
Mar 2024	278	3	1
Apr 2024	192	3	2
May 2024	278	2	2
Jun 2024	80	1	4
Jul 2024	124	3	1
Aug 2024	82	0	0
Sep 2024	100	8	0
Total	18851	24483	3172

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