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Autoimmune myasthenia gravis after cardiac surgery
  1. C Scoppetta1,2,
  2. P Onorati1,2,
  3. F Eusebi1,2,
  4. M Fini2,
  5. A Evoli3,
  6. A Vincent4
  1. 1Dipartimento di Fisiologia umana e Farmacologia, Università di Roma “La Sapienza”, Piazzale Aldo Moro 5, 00185, Rome, Italy
  2. 2Dipartimento di Scienze internistiche, Ospedale San Raffaele Pisana, Tosinvest Sanità, Rome, Italy
  3. 3Istituto di Neurologia, Università Cattolica, Rome, Italy
  4. 4Department of Clinical Neurology, University of Oxford, Oxford, UK
  1. Correspondence to: Professor C Scoppetta;

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Autoimmune myasthenia gravis (MG) is a heterogenous disorder. In young women, the thymus gland is often hyperplastic, and the patients respond well to thymectomy. However, in the increasing number of patients over the age of 40 years, predominantly men, thymic hyperplasia is uncommon, and there are no clear aetiological clues.1

We diagnosed MG in three male patients who had undergone cardiac surgery between three and ten weeks before developing symptoms. Table 1 summarises their main features. The patients presented with ocular, bulbar, and mild generalised weakness (Osserman classification …

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