You are here

Article Text

Article menu
Download PDFPDF
Short report
Atypical herpes type 2 encephalitis associated with normal MRI imaging
  1. N A Harrison1,
  2. B K MacDonald2,
  3. G Scott3,
  4. R Kapoor4
  1. 1Psychiatry, Maudsley Hospital, Denmark Hill, London, UK
  2. 2Neurology, Mayday Hospital, Croyden, Surrey, UK
  3. 3Microbiology, University College London Hospitals, UK
  4. 4Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
  1. Correspondence to Dr Kapoor, Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK;
 r.kapoor{at}ion.ucl.ac.uk

Abstract

We describe a case of chronic atypical herpes simplex type 2 encephalitis in an immunocompromised 68 year old man presenting with headache and cognitive changes without focal neurological or MRI findings. To our knowledge this is the first described case of herpes simplex encephalitis associated with normal MRI brain imaging and non-focal neurological examination. This further expands the range of clinical presentations that may be associated with herpes simplex encephalitis and emphasises the value of PCR for herpes simplex virus in the investigation of encephalitis regardless of imaging findings.

  • herpes simplex
  • encephalitis
  • immunosuppression

https://doi.org/10.1136/jnnp.74.7.974

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • Competing interests: none declared