Article Text
Statistics from Altmetric.com
Mirror movements may result from a primary motor efferent system dysfunction with secondary motor reorganisation. A profound dysfunction of the motor pathways has been reported in Parkinson’s disease (PD) during execution of motor tasks.1,2 Recent PET studies have demonstrated overactivation of ipsilateral motor areas in hemiparkinsonian patients.3,4 However, the clinical expression of ipsilateral cortical activation was not specifically investigated in previous reports. In this study, we explored the presence of mirror movements (MM) during standardised unilateral hand tasks in a series of 21 hemiparkinsonian patients.
Patients were divided into two groups: de novo patients (n=11), age 53.2 (7.5) years (mean (SD)), duration of evolution 1.8 years (range: 1–5 years), UPDRS III motor score 12 (5.7), affected side: left n=5, right n=6; and treated patients (n=10), age 59.8 (7.6) years, duration of evolution 3.7 (1.8) years (range: 2–7 years), UPDRS III motor score 14 (7.5), affected side: left n=4, right n=6, mean daily dose …