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  1. Geraint Fuller,
  2. Ian Bone
  1. Correspondence to:
 Dr GN Fuller, Department of Neurology, Gloucester Royal Hospital, Great Western Road, Gloucester GL1 3NN, UK; 

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This supplement tackles the lower levels of the nervous system, the peripheral nerves, the neuromuscular junction, and muscle diseases. Motor neurone disease/amyotrophic lateral sclerosis, a disorder of both upper and lower motor neurones, will be considered in a later supplement.

There are many diseases of nerve and muscle; a few are common, many are rare, a situation that often leaves neurologists with uncertainty as to how extensively to investigate their patients. Some of these conditions are treatable, though in none is this simple. Here we …

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