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Visual field constriction associated with vigabatrin: retinal nerve fiber layer photographic correlation
  1. H J Choi,
  2. D M Kim
  1. Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea
  1. Correspondence to:
 Dr D M Kim
 Department of Ophthalmology, Seoul National University Hospital, 28 Yongon-Dong, Chongno-Gu, Seoul 110-744, Korea;

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An 18 year old male who had been taking vigabatrin for complex partial seizure was referred for visual field testing. The cumulative vigabatrin dose was about 6.0 kg over the seven and a half year period. There were bilateral symmetric visual field constrictions with greater loss of the nasal field (fig 1). On the retinal nerve fibre layer (RNFL) photographs discernible RNFL losses in the peripheral retina with a relative preservation of papillomacular bundles were observed bilaterally (fig 2). RNFL thickness around the optic disc, …

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