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- Published on: 13 April 2016
- Published on: 13 April 2016
- Published on: 13 April 2016Authors' reply to Dr ConnemannShow More
Dear Editor
In reply to the comments by Dr Connemann [1]:
Although our study was designed to investigate rTMS add-on effects in an aggressive stimulation paradigm [2] we did not find a significant difference between the active group (n= 25) in comparison to sham (n=13) in a two week trial. Although we used aggressive parameters in an add-on setting neurocognitive measure even slightly improved in the acti...
Conflict of Interest:
None declared. - Published on: 13 April 2016Sufficient power to detect a slight effect?Show More
Dear Editor
The report by Hausmann et al.[1] adds to negative experiences with rTMS as an add-on strategy in patients with major depression.[2] However, again, the evidence is not completely convincing. In this study, only "slight" effects were expected, but the sample size did not appear to account for that. 25 vs. 13 patients may not suffice to detect - and even less to refute - slight effects.
Thi...
Conflict of Interest:
None declared.