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Brain tissue guided treatment supplementing ICP/CPP therapy after traumatic brain injury
  1. D Zygun
  1. Correspondence to:
 Dr D Zygun
 University Department of Anaesthesia, University of Cambridge, Box 93, Level 4, E block, Hills Road, Addenbrooke’s Hospital, Cambridge CB2 2QQ, UK; dzygunucalgary.ca

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The recent article by Meixensberger and colleagues comparing a brain tissue oxygen guided treatment protocol with a ICP/CPP protocol1 presents insufficient evidence to support the conclusion that PtiO2 guided cerebral perfusion management reduced cerebral hypoxic events following traumatic brain injury. Brain tissue oxygen levels can easily be modified through changes in FiO2.2,3 Although the authors indicated that changes in F …

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