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Correspondence
Traumatic brain injury as a risk factor for Alzheimer’s disease
  1. K A Jellinger
  1. Institute of Clinical Neurobiology, Kenyongasse 18, A-1070 Vienna, Austria; kurt.jellinger@univie.ac.at

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      In a recent systematic review of case control studies investigating head injury as a risk factor for Alzheimer’s disease (AD), Fleminger et al1 replicated the results of the meta-analysis by Mortimer et al2 in males (OR 2.29; 95% CI from 1.47 to 2.00) but not in females (OR 0.91; 95% CI from 0.56 to1.47). Their findings support in males only an association between a history of previous head injury and the risk of developing AD, but the study could not review the relation between head injury and ApoE gene status as risk factors for …

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