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Is it time to consider rationalising IFN-β treatment in individuals with multiple sclerosis?

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  • Conflict of interests: I have participated in meetings sponsored by and received honoraria from pharmaceutical companies marketing treatments for MS. I have or am participating in randomised controlled trials involving IFN-β-1b (Betaferon®, Schering), IFN-β-1a (Avonex®, Biogen), and Natalizumab (Antegren®, Biogen-Idec/Elan) in MS. I have also received honoraria for acting in the capacity as an advisor to various pharmaceutical companies who have drug development programmes for MS.