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Exposure to aluminium and the subsequent development of a disorder with features of Alzheimer’s disease
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  • Published on:
    Re: Alzheimer's Dementia and Aluminum in Drinking Water

    Dear Editor,

    Dr Russell Blaylock opens an interesting perspective with respect to the toxicity of the aluminofluoride complex as a potential factor in the Camelford aluminium sulphate incident. It may be relevant to note, therefore, that the key water sample taken at the height of the contamination contained not only 620mg/l of aluminium, but also 7 mg/l of fluoride, presumably present as a contaminant of the o...

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    Conflict of Interest:
    None declared.
  • Published on:
    Alzheimer's Dementia and Aluminum in Drinking Water

    Dear Editor,

    This case strengthens the correlation between aluminum in drinking water and Alzheimer's dementia. A number of studies have shown a relation between hyperphosporylation of tau and aluminum but of more interest is the observation that aluminum can activate brain microglia, which induces the release of toxic concentrations of inflammatory cytokines, eicosanoids, ROS, lipid peroxidation products and tw...

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    Conflict of Interest:
    None declared.