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Severe cerebral congophilic angiopathy coincident with increased brain aluminium in a resident of Camelford, Cornwall, UK
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  • Published on:
    Aluminum and development of Alzheimer's disease

    Dear Editor,

    I read the article on severe cerebral congophilic angiopathy coincident with increased brain aluminum (Al) in a resident of Camelford with interest(1).

    The elevation of Al appears to be significant, up to 23.00 ug/g in the present case being much higher than usual seen in human brain, however the elevation of Al noted in the similar case, a sample with 25.16 ug/g, would indicate Al may be m...

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    Conflict of Interest:
    None declared.
  • Published on:
    Camelford and aluminum sulfate-induced betaAPP gene expression

    Dear Editor,

    The recent paper by Exley and Esiri, describing the neuropathological examination of a 44 year old female affected by massive aluminum overload in the “Camelford incident”, defines what may be the first example of wide -scale early-onset beta-amyloid angiopathy by aluminum sulfate-induced overexposure (1). Time will tell. Indeed, two recent studies from our group further support a very active role for a...

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    Conflict of Interest:
    None declared.