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Clinimetric properties of a walking scale in peripheral neuropathy
  1. R C Graham1,
  2. R A C Hughes2
  1. 1Division of Applied Biomedical Research, King’s College London, London, UK
  2. 2Department of Clinical Neuroscience, King’s College London
  1. Correspondence to:
 Professor R A C Hughes
 Department of Clinical Neuroscience, King’s College London School of Medicine, Guy’s Hospital, London SE1 1UL, UK;{at}


Difficulty in walking is seen in many people with peripheral neuropathies, but walking ability is not comprehensively measured by commonly used outcome measures. The clinimetric properties of the 12-Item Multiple Sclerosis Walking Scale (MSWS-12, renamed the Walk-12) were investigated in 65 patients with peripheral neuropathies. Owing to its excellent internal consistency and reliability, and strong correlation with measures of physical and social function (r>0.8), the Walk-12 is recommended for measuring walking ability in peripheral neuropathies.

  • CIAP, chronic idiopathic axonal neuropathy
  • CIDP, chronic inflammatory demyelinating polyradiculoneuropathy
  • CMT, Charcot–Marie–Tooth disease
  • GBS, Guillain–Barré syndrome
  • MMN, multifocal motor neuropathy
  • MRC Sum Score, Medical Research Council Sum Score
  • ODSS, Overall Disability Sum Score
  • ONLS, Overall Neuropathy Limitations Scale
  • PDN, paraproteinaemic demyelinating neuropathy
  • SF-36 Questionnaire, 36-Item Short-Form Questionnaire
  • Walk-12, 12-Item Walking Scale

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  • See Editorial Commentary, p 899

  • This study was funded by the Guy’s and St Thomas’ Charity. Approval was granted by the Guy’s Hospital Research Ethics Committee and the Guy’s and St Thomas’ NHS Foundation Trust Audit Committee.

  • Competing interests: None.

  • Published Online First 30 March 2006

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