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Assessment of simple movements and progression of Huntington’s disease
  1. Jürgen Andrich,
  2. Carsten Saft,
  3. Natalie Ostholt,
  4. Thomas Müller
  1. Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse, Bochum, Germany
  1. Correspondence to:
 Dr T Müller
 Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, D-44791 Bochum, Germany; thomas.mueller{at}


Instrumental measurement of simple motion sequences reflects impairment in patients with Huntington’s disease (HD). The objectives were to study the progress of symptoms of HD and tapping results in 42 patients with HD, without symptomatic drug treatment over 3 years. Assessment moments were at baseline, and at years 1, 2 and 3. Unified Huntington’s Disease Rating Scale (UHDRS) total score and UHDRS arm score significantly increased. Motor test outcomes considerably worsened. Instrumental test results significantly correlated with both UHDRS scores at each assessment. Assessment of simple movement sequences is an additional simple method to follow impairment in patients with HD in addition to clinical rating.

  • HD, Huntington’s disease
  • UHDRS, Unified Huntington’s Disease Rating Scale

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  • Competing interests: None declared.

  • Published Online First 10 November 2006

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