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Funding: This study was supported by the Motor Neurone Disease Research Institute of Australia, as well as grants from the European Union (contract LSHM-CT-2003-503330, APOPIS), and the Middlemass family.
Competing interests: None.
Ethics approval: The protocols were approved by the human research ethics committees of Concord Hospital and Kings College.
Patient consent: Informed consent was obtained for publication of the details in this report.
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