Article Text

Download PDFPDF
Tongue pseudohypertrophy in idiopathic hypoglossal nerve palsy
  1. D Holle1,
  2. O Kastrup1,
  3. S-Y Sheu2,
  4. M Obermann1
  1. 1
    University Hospital Essen, Department of Neurology, Essen, Germany
  2. 2
    University Hospital Essen, Institute of Pathology and Neuropathology, Essen, Germany
  1. Correspondence to Dr D Holle, University Hospital Essen, Department of Neurology, Hufelandstrasse 55, 45122 Essen, Germany; dagny.holle{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Hypoglossal nerve palsy is a common finding in neurological diseases when associated with other cranial nerve palsy or further pathology. The underlying pathology of its occurrence is very diverse. Keane analysed 100 cases of hypoglossal nerve palsy and found that most of them were caused by tumours. Different common causes were trauma, medullary infarctions, multiple sclerosis, Guillain–Barré neuropathy and infection.1 In contrast, isolated hypoglossal nerve palsy is a rare feature.

In general, hypoglossal nerve palsy, like other more common causes of neurogenic denervation, leads to atrophy of the affected muscle.2 However, some cases of motor denervation induce …

View Full Text


  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and Peer review Not commissioned; externally peer reviewed.