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Prospective study of chemical exposures and amyotrophic lateral sclerosis
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- Published on: 13 April 2016
- Published on: 13 April 2016Neurotoxicity of formaldehydeShow More
Dear Editor,
Although the association of the formaldehyde exposure with the etiology of ALS may be due to bias, the careful investigation of Weisskopf et al. (1) is thought-provoking.
Methanol and its first metabolite are neurotoxic (2, 3) because their common end metabolite formic acid is an inhibitor of the cytochrome oxidase in the mitochondrial respiratory chain (3).
The neurochemical mech...
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None declared.