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Epstein–Barr virus is associated with grey matter atrophy in multiple sclerosis
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  • Published on: 13 April 2016
    Epstein-Barr virus may cause Multiple Sclerosis through involvement of the venous system.

    Dear Editor,

    I read the article by Zivadinov (1) with reference to the association of Epstein-Barr virus (EBV) to gray matter atrophy in multiple sclerosis (MS) patients.

    Accumulation of EBV infected B cells in meninges and perivascular regions of MS lesions in 21 or 22 patients with MS (2) was noted as well, indicating direct involvement of the brain and perivascular spaces by EBV in MS patients.....

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    Conflict of Interest:
    None declared.