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Acute Wernicke’s encephalopathy with hyperechogenic corpora mammillaria in brain sonography
  1. A Günther1,
  2. D Berg2,
  3. F Joachimski1,
  4. A Ragoschke-Schumm3,
  5. C Redecker1
  1. 1
    Department of Neurology, Friedrich-Schiller-University, Jena, Germany
  2. 2
    Hertie-Institute for Clinical Brain Research and Department of Medical Genetics, University of Tübingen, Germany
  3. 3
    Department of Neuroradiology, Friedrich-Schiller-University, Jena, Germany
  1. Correspondence to Dr A Günther, Department of Neurology, Friedrich-Schiller-University, Erlanger Allee 101, D-07747 Jena, Germany; Albrecht.guenther{at}

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A 50-year-old woman presented with an acute onset of nystagmus, ataxia and drowsiness as the classical triad of Wernicke’s encephalopathy (WE).1 Additionally, she developed psychotic symptoms and disorientation as a sign of coincidental Korsakoff’s syndrome. MRI revealed typical changes in the corpora mammillaria (CM) as well as in the periaqueductal grey (fig 1A) and periventricular zone, which showed regression over the following 2 months (fig 1B). The patient’s medical history included a gastrectomy for gastric cancer (5 months prior …

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  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and Peer review Not commissioned; externally peer reviewed.