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Recurrent ptosis due to myopathy of the levator palpebrae superioris
  1. A Petzold1,
  2. P J Luthert2,
  3. J R O Collin3,
  4. G T Plant4
  1. 1UCL Institute of Neurology, Institute of Neurology, Queen Square, London, UK
  2. 2Pathology Department, Institute of Ophthalmology, London, UK
  3. 3Moorfields Eye Hospital, London, UK
  4. 4The National Hospital for Neurology and Neurosurgery, London, UK
  1. Correspondence to Dr A Petzold, Institute of Neurology, Queen Square, London, WC1N 3BG, UK; a.petzold{at}


The authors report the 10-year follow-up of a case with a recurrent ptosis affecting both eyelids independently. The histology of the levator palpebrae superioris and Müller's muscle was consistent with a localised myopathic process. A therapeutic response to acetazolamide suggests that ion-channel dysfunction may be the underlying cause for this new myopathy.

  • Lid crease sign
  • myopathy
  • ptosis

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  • Competing interests None.

  • Patient consent Obtained.