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Multiple spinal intramedullary cavernomas with vascular skin venus or ‘Cobb syndrome’: a case report
  1. S Gatzonis,
  2. G Strantzalis,
  3. A Siatouni,
  4. E Boviatsis,
  5. D E Sakas
  1. Department of Neurosurgery, University of Athens Medical School, “Evangelismos” General Hospital, Athens, Greece
  1. Correspondence to Dr S Gatzonis, Department of Neurosurgery, “Evangelismos” Hospital, Athens Medical School, 45-47 Ipsilantou St, Athens, Greece; sgatzon{at}

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Cobb syndrome consists of a vascular skin nevus associated with an angioma in the spinal cord.1 Cavernous angiomas (CAs) account for 5–16% of all spinal vascular malformations.2 The spinal cord is a rare site for CAs.1

Mean age at diagnosis is 36.4 years, with a peak between the third and fifth decades. Women make up 70% of all patients.1 3 Lesions are most frequently localised at the cervical and thoracic spinal cord.3 Mean size at diagnosis is 1.7 cm.3

We present a patient diagnosed as having multiple intramedullary thoracic CAs.

Case report

A 32-year-old woman presented with weakness and numbness of the lower extremities. She described slight …

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  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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