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Large-scale SOD1 mutation screening provides evidence for genetic heterogeneity in amyotrophic lateral sclerosis
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  • Published on: 17 May 2010
    Superoxide dismutase in brain

    Dear Editor,

    I have read with the greatest interest the large investigation on the mutated superoxide dismutase (SOD) frequency in the Dutch amyotrophic lateral sclerosis patients (1). The results seem to show that is very rare in the Netherlands, or it may be only an epiphenomenon from the point of view of the disease pathogenesis.

    This conclusion could be reconciled with the circumstance that a large...

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    Conflict of Interest:
    None declared.