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An evaluation of neurophysiological criteria used in the diagnosis of motor neuron disease
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  • Published on:
    Awaji Shima criteria for motor neuron disease

    Dear Sir, We write in response to the rapid response by Kleine et al. The disparity between the sensitivity of El Escorial in our study (1) and the work by Boekestein et al (2) and de Carvalho (3), we suggest is as a result of the differing neurophysiology protocols. Boekestein et al and de Carvalho use at least 3 times the insertions used in our standard protocols. The protocol used in our study is tailored for everyday...

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    Conflict of Interest:
    None declared.
  • Published on:
    Awaji criteria: too complex?
    • Bert U. Kleine, Resident
    • Other Contributors:
      • Werner A Boekestein, Ilse M P Arts, Machiel J Zwarts, Helenius Jurgen Schelhaas

    Dear Editor,

    With great interest we read the retrospective application of the Awaji criteria (1) by Douglas et al. (2). In this paper the authors validated the Awaji criteria in a routine clinical setting. A remarkable finding is that after EMG assessment only one patient could be classified as probable laboratory supported ALS. Consequently a low sensitivity of the revised El Escorial criteria was found. This...

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    Conflict of Interest:
    None declared.