Mitoxantrone prior to interferon beta-1b in aggressive relapsing multiple sclerosis: a 3-year randomised trial

G Edan; G Comi; E Le Page; E Leray; M A Rocca; M Filippi; for The French–Italian Mitoxantrone Interferon-beta-1b Trial Group

doi:10.1136/jnnp.2010.229724

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Research paper

Mitoxantrone prior to interferon beta-1b in aggressive relapsing multiple sclerosis: a 3-year randomised trial

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	Abstract	Full	Pdf
Mar 2011	95	5	25
Apr 2011	160	6	35
May 2011	60	26	33
Jun 2011	61	18	11
Jul 2011	51	11	12
Aug 2011	26	8	9
Sep 2011	26	13	12
Oct 2011	40	8	14
Nov 2011	410	30	116
Dec 2011	191	19	52
Jan 2012	215	16	32
Feb 2012	125	11	16
Mar 2012	108	3	11
Apr 2012	87	11	9
May 2012	62	9	18
Jun 2012	80	13	12
Jul 2012	69	9	13
Aug 2012	55	8	12
Sep 2012	84	13	15
Oct 2012	64	5	7
Nov 2012	54	18	15
Dec 2012	46	4	6
Jan 2013	72	3	4
Feb 2013	42	8	8
Mar 2013	25	5	7
Apr 2013	25	1	2
May 2013	33	3	4
Jun 2013	24	7	5
Jul 2013	24	3	6
Aug 2013	29	1	3
Sep 2013	15	2	1
Oct 2013	23	6	8
Nov 2013	31	9	4
Dec 2013	16	3	4
Jan 2014	18	6	9
Feb 2014	22	2	5
Mar 2014	40	8	9
Apr 2014	32	1	1
May 2014	34	15	13
Jun 2014	33	4	4
Jul 2014	41	2	3
Aug 2014	14	5	5
Sep 2014	15	2	1
Oct 2014	12	6	3
Nov 2014	13	7	11
Dec 2014	19	5	6
Jan 2015	7	3	4
Feb 2015	8	4	2
Mar 2015	16	2	4
Apr 2015	9	10	2
May 2015	17	4	2
Jun 2015	19	1	2
Jul 2015	16	8	3
Aug 2015	15	3	2
Sep 2015	32	2	4
Oct 2015	17	2	3
Nov 2015	11	6	8
Dec 2015	21	6	4
Jan 2016	12	1	1
Feb 2016	24	0	1
Mar 2016	17	5	4
Apr 2016	14	4	4
May 2016	21	3	3
Jun 2016	10	1	1
Jul 2016	11	3	4
Aug 2016	18	4	5
Sep 2016	70	7	9
Oct 2016	29	3	7
Nov 2016	17	4	6
Dec 2016	19	4	3
Jan 2017	26	2	6
Feb 2017	33	4	7
Mar 2017	27	3	3
Apr 2017	19	3	3
May 2017	26	6	6
Jun 2017	38	4	5
Jul 2017	58	10	5
Aug 2017	55	6	2
Sep 2017	31	5	3
Oct 2017	74	3	2
Nov 2017	70	7	7
Dec 2017	123	9	10
Jan 2018	83	12	3
Feb 2018	88	8	4
Mar 2018	28	4	1
Apr 2018	38	4	3
May 2018	49	5	3
Jun 2018	40	4	1
Jul 2018	33	1	2
Aug 2018	31	3	2
Sep 2018	38	2	1
Oct 2018	66	1	1
Nov 2018	60	6	4
Dec 2018	22	0	0
Jan 2019	38	2	1
Feb 2019	34	1	0
Mar 2019	22	4	0
Apr 2019	29	4	3
May 2019	24	2	2
Jun 2019	35	1	1
Jul 2019	42	6	6
Aug 2019	57	3	2
Sep 2019	35	1	3
Oct 2019	63	9	11
Nov 2019	15	0	0
Dec 2019	28	5	3
Jan 2020	37	5	3
Feb 2020	45	5	2
Mar 2020	28	6	1
Apr 2020	23	7	2
May 2020	46	3	4
Jun 2020	27	0	0
Jul 2020	26	4	1
Aug 2020	26	3	2
Sep 2020	36	2	1
Oct 2020	17	10	1
Nov 2020	61	5	2
Dec 2020	41	2	3
Jan 2021	51	1	2
Feb 2021	48	0	1
Mar 2021	46	4	3
Apr 2021	29	1	0
May 2021	17	0	0
Jun 2021	0	0	3
Jul 2021	1	0	0
Aug 2021	1	1	1
Sep 2021	1	1	1
Oct 2021	38	0	1
Nov 2021	39	0	0
Dec 2021	32	0	3
Jan 2022	43	1	0
Feb 2022	60	3	3
Mar 2022	47	2	1
Apr 2022	41	3	1
May 2022	44	2	1
Jun 2022	53	3	2
Jul 2022	46	3	2
Aug 2022	50	1	0
Sep 2022	59	1	1
Oct 2022	114	6	2
Nov 2022	52	7	2
Dec 2022	47	3	2
Jan 2023	72	4	1
Feb 2023	95	2	0
Mar 2023	87	0	0
Apr 2023	14	1	3
May 2023	29	3	0
Jun 2023	17	0	0
Jul 2023	39	1	0
Aug 2023	17	0	0
Sep 2023	58	4	1
Oct 2023	154	2	0
Nov 2023	186	3	0
Dec 2023	58	3	1
Jan 2024	55	6	2
Feb 2024	40	3	1
Mar 2024	36	1	0
Apr 2024	48	3	2
May 2024	59	3	1
Jun 2024	46	2	1
Jul 2024	23	0	0
Aug 2024	43	3	2
Total	7397	757	884

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