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Funding This work was undertaken at UCLH/UCL who received a proportion of funding from the Department of Health's NIHR Biomedical Research Centres funding scheme. The Dementia Research Centre is an Alzheimer's Research Trust Coordinating Centre. This work was also funded by the Medical Research Council UK. JW has received research support from the Wellcome Trust (Intermediate Clinical Fellowship).
Competing interests None.
Patient consent Obtained.
Ethics approval This study was conducted with the approval of the National Hospital for Neurology and Neurosurgery local ethics committee.
Provenance and peer review Not commissioned; externally peer reviewed.