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11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt–Jakob disease

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  • Funding This work was supported by the Department of Health (England) through funding of the National Prion Monitoring Cohort study and by the UK Medical Research Council. Some of this work was undertaken at University College London Hospitals/University College London, which received a proportion of funding from the National Institute for Health Research Comprehensive Biomedical Research Centres funding scheme.

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval This study was conducted with the approval of the NHNN and ION Local Research Ethics Committee.

  • Provenance and peer review Not commissioned; externally peer reviewed.