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Funding This work was supported by the Medical Research Council Translational Neuromuscular Centre. RH is supported by the Medical Research Council (G1000848) and the Academy of Medical Sciences, UK (BH090164). PFC is a Wellcome Trust Senior Fellow in Clinical Science, and also receives funding from the Parkinson's Disease Society (UK), the Medical Research Council Translational Muscle Centre and the UK NIHR Biomedical Research Centre in Ageing and Age-related Disease.
Competing interests None.
Patient consent Obtained.
Ethics approval This study was approved and performed under the ethical guidelines issued by our institutions for clinical studies.
Provenance and peer review Not commissioned; externally peer reviewed.
Data sharing statement The corresponding author declares that all authors and contributors have agreed to conditions about data sharing noted on the Authorship Agreement Form.
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