Footnotes

• Author note Cossins and colleagues6 have recently reported mutations in the other glycosylation enzymes, ALG2 and ALG14, in seven patients with a limb-girdle pattern of muscle weakness with eye, facial, and bulbar muscles largely spared and with favorable responses to cholinesterase inhibitors.

• Competing interests None.

• Provenance and peer review Commissioned; not externally peer reviewed.