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Or Martinez-Lapiscina et al report results of a clinical trial of two different versions of a Mediterranean type diet (MedDiet)1 versus a standard low fat diet. The parent trial (PREDIMED) was focused on prevention of cardiovascular disease but cognitive outcomes (using the MMSE and the Clock Drawing Test) were the focus of this report. After a mean of 6½ years, cognitive differences (∼half a point in MMSE) in favour of MedDiet plus olive oil and trends of cognitive differences in favour of MedDiet plus nuts were noted. The associations were present (or even strengthened) after adjusting for multiple potential confounders.
The exploration of the relation of MedDiet with neurological diseases has started only very recently and …
Funding US Federal NIA grant AG028506, Alzheimer's Association grant IIRG-04-1353.
Competing interests None.
Provenance and peer review Commissioned; internally peer reviewed.