The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease

Roger A Barker; Sarah L Mason; Timothy P Harrower; Rachel A Swain; Aileen K Ho; Barbara J Sahakian; Raj Mathur; Sohier Elneil; Steven Thornton; Carrie Hurrelbrink; Richard J Armstrong; Pam Tyers; Emma Smith; Adrian Carpenter; Paola Piccini; Yen F Tai; David J Brooks; Nicola Pavese; Colin Watts; John D Pickard; Anne E Rosser; Stephen B Dunnett; the NEST-UK collaboration

doi:10.1136/jnnp-2012-302441

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The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease

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Roger A Barker Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK Department of Clinical Neuroscience, University of Cambridge Medical School, Addenbrooke's Hospital, Cambridge UK PubMed articles Google scholar articles
Sarah L Mason Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Timothy P Harrower Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK Department of Clinical Neuroscience, University of Cambridge Medical School, Addenbrooke's Hospital, Cambridge UK PubMed articles Google scholar articles
Rachel A Swain Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Aileen K Ho Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Barbara J Sahakian Department of Psychiatry, University of Cambridge Medical School, Addenbrooke's Hospital, Cambridge UK PubMed articles Google scholar articles
Raj Mathur PubMed articles Google scholar articles
Sohier Elneil Department of Obstetrics and Gynaecology, University of Cambridge Medical School, Addenbrooke's Hospital, Cambridge, UK PubMed articles Google scholar articles
Steven Thornton Department of Obstetrics and Gynaecology, University of Cambridge Medical School, Addenbrooke's Hospital, Cambridge, UK PubMed articles Google scholar articles
Carrie Hurrelbrink Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Richard J Armstrong Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Pam Tyers Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Emma Smith Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Adrian Carpenter Department of Neurosurgery, University of Cambridge Medical School, Addenbrooke's Hospital, Cambridge UK PubMed articles Google scholar articles
Paola Piccini Centre for Neuroscience, Division of Experimental Medicine, Department of Medicine, Imperial College London, London, UK PubMed articles Google scholar articles
Yen F Tai Centre for Neuroscience, Division of Experimental Medicine, Department of Medicine, Imperial College London, London, UK PubMed articles Google scholar articles
David J Brooks Centre for Neuroscience, Division of Experimental Medicine, Department of Medicine, Imperial College London, London, UK PubMed articles Google scholar articles
Nicola Pavese Centre for Neuroscience, Division of Experimental Medicine, Department of Medicine, Imperial College London, London, UK PubMed articles Google scholar articles
Colin Watts Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK Department of Neurosurgery, University of Cambridge Medical School, Addenbrooke's Hospital, Cambridge UK PubMed articles Google scholar articles
John D Pickard Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK Department of Neurosurgery, University of Cambridge Medical School, Addenbrooke's Hospital, Cambridge UK PubMed articles Google scholar articles
Anne E Rosser Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK Brain Repair Group, School of Biosciences and Medicine, Cardiff University, Wales, UK PubMed articles Google scholar articles
Stephen B Dunnett Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK Brain Repair Group, School of Biosciences and Medicine, Cardiff University, Wales, UK PubMed articles Google scholar articles
the NEST-UK collaboration
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Correspondence to Dr Roger Barker, Cambridge Centre for Brain Repair, University of Cambridge, Forvie Site, Cambridge CB2 0PY, UK; rab46{at}cam.ac.uk

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Barker RA, Mason SL, Harrower TP, et al

The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease

Journal of Neurology, Neurosurgery & Psychiatry 2013;84:657-665.

Publication history

Received April 26, 2012
Revised September 18, 2012
Accepted December 18, 2012
First published January 23, 2013.

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May 07, 2013

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