Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Bickerstaff brainstem encephalitis (BBE) is characterised by acute ophthalmoplegia, ataxia, and some features suggesting CNS involvement such as consciousness disturbance. In 1951, Bickerstaff and Cloake described three patients in their original report entitled ‘Mesencephalitis and rhomboencephalitis’, and in 1957 Bickerstaff expanded his series to eight patients and proposed the condition ‘brainstem encephalitis’, subsequently termed ‘BBE’. Between the two publications, in 1956 Miller Fisher described three patients with “an unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia)”; this condition has been widely recognised as Fisher syndrome (FS). A detailed historical perspective of BBE and FS was presented in a review …
Contributors SK, SM and MM prepared the manuscript, and contributed equally to the article.
Competing interest None.
Provenance and peer review Commissioned; internally peer reviewed.