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The Author reply, We thank Dr Ramesh and colleagues in their letter1 for drawing our attention to their recent, important paper,2 showing very early, preclinical abnormalities in a Zebrafish model of amyotrophic lateral sclerosis (ALS), which we overlooked in our recent review, ‘Amyotrophic lateral sclerosis: a long preclinical period?’3 The Zebrafish findings are completely supportive …
Competing interests None.
Provenance and peer review Commissioned; internally peer reviewed.
jnnp-2014-308288—A zebrafish model exemplifies the long pre-clinical period of Motor Neuron Disease