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Movement disorders
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Which target is best for patients with Parkinson's disease? A meta-analysis of pallidal and subthalamic stimulation
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  • Published on: 13 April 2016
    Reply to Letter: Which target is best for patients with Parkinson's disease? A meta-analysis of pallidal and subthalamic stimulation
    • Wataru Sako, assistant professor
    • Other Contributors:
      • Yoshimichi Miyazaki, Yuishin Izumi, Ryuji Kaji

    We are pleased that Dr. Cyron agrees with our statement. Although our meta-analysis revealed that depression was more frequent in STN DBS relative to GPi DBS, additional randomized trials which investigate long- term outcome including UPDRS, quality of life and adverse events are required to determine which target is more appropriate for patients with PD. We hope our findings and suggestions would be useful for future stu...

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    Conflict of Interest:
    None declared.
  • Published on: 13 April 2016
    STN revisted

    This is a timely contribution to an issue overdue. STN-stimulation has been the undisputed mainstay of DBS for Pakinson's disease more than a decade. Reports on deleterious side effects mainly in the field of cognition and emotion however accumulate. While the rather subtle effects on cognitive abilities have been the subject of a plethora of publications, changes in personality and behavior remain underreported. Yet it...

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    Conflict of Interest:
    None declared.