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Contributors SJ, DRT and ACL made substantial contributions to the conception or design of the work; or the acquisition, analysis or interpretation of data for the work. DRT and ACL were involved in the drafting of the work or revising it critically for important intellectual content; both gave final approval of the version to be published.
Funding This study was supported by the MND-Net (Grant No.: BMBF Förderkennzeichen 01GM1103A; ACL, DRT) and the Alzheimer Forschung Initiative (Grant No.: AFI #13803; DRT).
Competing interests DRT received consultant Honoraria from GE-Healthcare, Covance Laboratories, and Simon Kucher & Partners, and collaborated with Novartis Pharma.
Patient consent Obtained.
Ethics approval Ethics Committee of the University of Ulm.
Provenance and peer review Not commissioned; externally peer reviewed.