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Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system (CNS) characterised by encephalopathy and other neurological manifestations. ADEM is a heterogeneous syndrome predominantly found in the paediatric population. ADEM usually takes a monophasic course, but some patients have a relapsing disease. Patients diagnosed with ADEM have multifocal CNS lesions including of the spinal cord and/or optic nerves. Therefore, ADEM should be distinguished from other diseases such as multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD). …
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