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Contributors MS: acquisition of data; design and conceptualisation of the study; drafting the manuscript. CK and TBH: acquisition of data; revising the manuscript. LS: conceptualisation and supervision of the study; revising the manuscript.
Competing interests MS received honoraria from Actelion Pharmaceuticals.
Patient consent Obtained.
Ethics approval Ethics Committee of the University of Tübingen, Germany.
Provenance and peer review Not commissioned; externally peer reviewed.
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