Footnotes

• Contributors All authors made substantial contribution to the patient's clinical care and data collections. AMF, JWB, JJVG and SMS had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the analysis. SMS was involved in study concept and design. AMF, SMS, JJVG and JWB were involved in acquisition of data. AMF and JWB were involved in drafting of the manuscript. AMF, JJVG, JWB and SMS were involved in critical revision of the manuscript for important intellectual content.

• Competing interests None.

• Patient consent Obtained.

• Provenance and peer review Not commissioned; externally peer reviewed.