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Cognitive neurology
Review
A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome: systematic review
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  • Published on: 10 December 2018
    Re: A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome
    • Viraj Bharambe, Specialist Registrar in Neurology Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    • Other Contributors:
      • John C Williamson, Specialist Registrar in Neurology
      • Andrew J Larner, Consultant Neurologist

    Re: A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome

    Viraj Bharambe Specialist registrar in neurology
    John C Williamson Specialist registrar in neurology
    Andrew J Larner Consultant Neurologist

    Cognitive Function Clinic
    Walton Centre for Neurology and Neurosurgery
    Lower Lane
    Fazakerley
    Liverpool
    L9 7LJ
    UK
    e-mail: a.larner@thewaltoncentre.nhs.uk

    Teodoro et al. present evidence for shared cognitive symptoms in fibromyalgia, chronic fatigue syndrome, and functional neurological disorders, and hypothesize that functional cognitive disorders (FCD) may share similar symptoms.1 We present data which speak to this issue.

    We have previously reported preliminary data examining performance on the mini-Addenbrooke’s Cognitive Examination (MACE) by patients diagnosed with fibromyalgia2 as part of a larger study of MACE.3 Here, we update these data for fibromyalgia patients (n = 17; F:M = 17:0; age range 33-56 years, median 49) and compare them to MACE performance by patients diagnosed with FCD (n = 43; F:M = 18:25; age range 28-82 years, median 58).4

    There was no statistical difference (p > 0.1) in the proportions of patients scoring below the two cut-off scores (≤21/30, ≤25/30) defined in the index MACE report.5 Looking at MACE subscores (Attention, Registration,...

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    Conflict of Interest:
    None declared.