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Contributors FM designed the research. JYJ conducted the research. RJM and YPZ provided essential reagents. JH and XXH performed the statistical analysis. JH wrote the paper. All authors revised the manuscript and approved the final version to be published.
Funding This study was supported by the National Natural Science Foundation of China (grant number: 81573148), the Natural Science Foundation of Tianjin Medical University (grant number: 2110-2GW034) and the Tianjin Science and Technology Support Program (grant number: 15ZCZDSY01040).
Disclaimer All inferences, opinions and conclusions drawn in this publication are those of the authors, and do not reflect the opinions or policies of the data steward(s).
Competing interests None declared.
Patient consent Obtained.
Ethics approval This study adheres to the principles of the Declaration of Helsinki. The protocol was approved by the Ethics Committee of Tianjin Medical University, China.
Provenance and peer review Not commissioned; externally peer reviewed.
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