Footnotes

• Contributors All authors contributed to this manuscript and meet the criteria for authorship.

• Funding This research was supported by the Intramural Research Programs of the National Institute of Neurological Disorders and Stroke and the National Institute of Allergy and Infectious Diseases at the National Institutes of Health.

• Competing interests PRW has a cooperative research and development agreement with Matinas BioPharma regarding an oral amphotericin formulation.

• Patient consent Obtained.

• Ethics approval NIH Institutional Review Board.

• Provenance and peer review Not commissioned; externally peer reviewed.