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A rapid whole body muscle MRI protocol is sensitive to disease progression in motor neuron disease.
As part of the evolution of neuromuscular medicine, there has been a move towards tools that can objectively measure change in the disease without relying on relatively insensitive or subjective clinical measures. Motor neuron disease (MND) has a wide array of potential clinical phenotypes and disease progression can be unpredictable between individuals.1 Clinical instruments to measure MND have well-defined limitations.2 3 For these reasons, it is necessary to develop objective non-clinical measures of disease progression in MND.
In their JNNP paper, Dr Jenkins and colleagues have advanced muscle MRI as a potential biomarker of MND progression.4 The authors performed whole body T2-weighted imaging on a cohort of patients with MND and demonstrated an …
Contributors NGS wrote this editorial without other contributors.
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.
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