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Contributors MM drafted this article, and SK and FP made critical revision of the article for important intellectual content.
Funding This work was supported in part by the Health and Labour Sciences Research Grant on Intractable Diseases (Neuroimmunological Diseases) from the Ministry of Health, Labour and Welfare of Japan, and by Deutsche Forschungsgemeinschaft (DFG Exc 257 to FP).
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.