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AEDs or no AEDs during pregnancy? That is the question
  1. Richard F M Chin1,2
  1. 1 Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh, UK
  2. 2 Department of Paediatric Neurosciences, Royal Hospital for Sick Children, Edinburgh, UK
  1. Correspondence to Dr Richard F M Chin, Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh EH8 9YL, UK; rchin{at}staffmail.ed.ac.uk

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Health informatics can help with the answer

Lacey and colleagues take the innovative approach of using linkage of routine-collected health and national education data to carry out a matched case–control study to assess educational attainment of children born to mothers with epilepsy1. Their main finding was in utero exposure to antiepileptic drugs (AED) in combination, or sodium valproate alone, is associated with a significant decrease in attainment in national educational tests for 7-year-old children compared with both the matched control group and the all-Wales national average. Arguably, at first glance, this may not seem like news per se but there are several points that make it highly noteworthy.

  • Previous studies have …

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